Acanthosis nigricans is one of the most common skin signs of obesity and hyperinsulinism and is a valuable predictor of insulin resistance in obese children. Patients with both obesity and acanthosis nigricans, compared with those with obesity alone, tend to have higher body mass indexes and increased fasting and evening insulin levels.Early recognition and intervention are crucial to avoid complications of insulin resistance. The general pediatrician is in the best position to perform the...

The following studies were reported at American Diabetes Association’s 70th Scientific Sessions in Orlando, Florida, on 25-29 June 2010, and were published in the American Diabetes Association meeting Special Issue of The Lancet. New diabetes drug acts independently of insulin, improves blood glucose control and lowers bodyweight Once weekly exenatide for type 2 diabetes is more convenient and induces better blood sugar control, and more weight loss, than standard second-line treatment...