15-May-2012

All mammalian cells express 3 closely related Ras proteins, termed H-Ras, K-Ras, and N-Ras, that...

15-May-2012

Melanomas and other cancers that do not express argininosuccinate synthetase (AS), the...

15-May-2012

Gastric cancer is the most common cancer in Asia and most developing countries. Despite the use of...

15-May-2012

Although oncolytic virotherapy is a promising anticancer therapy, antitumor efficacy is hampered...

15-May-2012

A number of cancers predominantly metastasize to bone, due to its complex microenvironment and...

15-May-2012

In an effort to develop cancer therapies that maximize cytotoxicity, while minimizing unwanted...

15-May-2012

EGFRvIII is a tumor-specific variant of the epidermal growth factor receptor (EGFR). Although...

15-May-2012

Many solid malignant tumors arise on a background of inflamed and/or fibrotic tissues, features...

15-May-2012

Increasing evidence suggests that HER2-amplified breast cancer cells use HER3/ErbB3 to drive...

15-May-2012

Pancreatic cancer is an aggressive disease with poor prognosis, due, in part, to the lack of...